Wednesday, 21 November, 2018

Women who wake up early "at lower risk of developing breast cancer"

Reham Afandi Reham Afandi
Anna Jefferson | 08 November, 2018, 04:03

Interestingly, the study also found that sleeping longer isn't necessarily better, as the analysis showed that women who slept longer than the recommended seven to eight hours per night increased their chances of being diagnosed with breast cancer by 20% per additional hour.

In the Mendelian randomization analysis, they found approximately one less person per 100 will develop breast cancer if they have a morning preference compared with people who have an evening preference.

Self-reported preferences for mornings or evenings (by their own definition of that preference) were recordedin more than 180,000 women, led by Dr. Rebecca Richmond, research fellow in the Cancer Research UK Integrative Cancer Epidemiology Program and the Epidemiology Unit at the University of Bristol, and presented Tuesday at the NCRI Cancer Conference in Glasgow.

Around one in seven women in the United Kingdom will develop breast cancer in their lifetime.

The team concluded that the study shows consistent evidence for a protective effect of morning preference, and suggestive evidence for an adverse effect of sleep duration on breast cancer risk.

And those who are sharper in the evening may have had more disrupted sleep, which could affect the risk of cancer.

Because these bits of DNA are set at birth and are not linked to other known causes of cancer, like obesity, it means the researchers are reasonably confident body clocks are involved in cancer.

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Does the pill give you breast cancer? Researchers then mapped the genetic variations between the earlier risers and the night owls and compared it with that to the risk of developing cancer.

Richmond stressed that the 48% lower risk was identified among "extreme" cases, where people identified themselves as "definite" morning people out of the five categories they could chose from - definite morning, more morning than evening, neither, more evening than morning, definite evening.

Dr Richmond and her colleagues are planning to investigate the mechanisms underlying the effects of different sleep characteristics on the risk of developing breast cancer.

"We know already that night shift work is associated with worse mental and physical health".

The study was funded by Cancer Research UK and the Medical Research Council. About 5 per cent of women with breast cancer have inherited a gene linked to the condition.

The findings have been published on researchers' website bioRxiv but have not yet gone through scientific peer review.

However, cancer experts say modifying your sleep patterns probably won't have a significant impact on your cancer risk.

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